Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity

Ademola Adetokunbo Oyagbemi; Olumuyiwa Abiola Adejumobi; Theophilus Aghogho Jarikre; Olumide Samuel Ajani; Ebunoluwa Racheal Asenuga; Idayat Titilayo Gbadamosi; Aduragbenro Deborah A. Adedapo; Abimbola Obemisola Aro; Blessing Seun Ogunpolu; Fasilat Oluwakemi Hassan; Olufunke Olubunmi Falayi; Iyanuoluwa Omolola Ogunmiluyi; Temidayo Olutayo Omobowale; Oluwatosin Adetola Arojojoye; Olufunke Eunice Ola-Davies; Adebowale Benard Saba; Adeolu Alex Adedapo; Benjamin Obukowho Emikpe; Matthew Olugbenga Oyeyemi; Sanah Malomile Nkadimeng; Lyndy Joy McGaw; Prudence Ngalula Kayoka-Kabongo; Oluwafemi Omoniyi Oguntibeju; Momoh Audu Yakubu

doi:10.1007/s12011-021-02722-1

Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity

Ademola Adetokunbo Oyagbemi, Olumuyiwa Abiola Adejumobi, Theophilus Aghogho Jarikre, Olumide Samuel Ajani, Ebunoluwa Racheal Asenuga, Idayat Titilayo Gbadamosi, Aduragbenro Deborah A. Adedapo, Abimbola Obemisola Aro, Blessing Seun Ogunpolu, Fasilat Oluwakemi Hassan, Olufunke Olubunmi Falayi, Iyanuoluwa Omolola Ogunmiluyi, Temidayo Olutayo Omobowale, Oluwatosin Adetola Arojojoye, Olufunke Eunice Ola-Davies, Adebowale Benard Saba, Adeolu Alex Adedapo, Benjamin Obukowho Emikpe, Matthew Olugbenga Oyeyemi, Sanah Malomile NkadimengLyndy Joy McGaw, Prudence Ngalula Kayoka-Kabongo, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu

Engineering

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1220-1236
Number of pages	17
Journal	Biological Trace Element Research
Volume	200
Issue number	3
DOIs	https://doi.org/10.1007/s12011-021-02722-1
State	Published - Mar 2022

ASJC Scopus Subject Areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Clinical Biochemistry
Inorganic Chemistry
Biochemistry, medical

Keywords

Antihypertensive
Apoptosis
Cell signalling
Hypertension
Oxidative stress
Sodium fluoride toxicity

Access to Document

10.1007/s12011-021-02722-1

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Oyagbemi, A. A., Adejumobi, O. A., Jarikre, T. A., Ajani, O. S., Asenuga, E. R., Gbadamosi, I. T., Adedapo, A. D. A., Aro, A. O., Ogunpolu, B. S., Hassan, F. O., Falayi, O. O., Ogunmiluyi, I. O., Omobowale, T. O., Arojojoye, O. A., Ola-Davies, O. E., Saba, A. B., Adedapo, A. A., Emikpe, B. O., Oyeyemi, M. O., ... Yakubu, M. A. (2022). Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity. Biological Trace Element Research, 200(3), 1220-1236. https://doi.org/10.1007/s12011-021-02722-1

Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity. / Oyagbemi, Ademola Adetokunbo; Adejumobi, Olumuyiwa Abiola; Jarikre, Theophilus Aghogho et al.
In: Biological Trace Element Research, Vol. 200, No. 3, 03.2022, p. 1220-1236.

Research output: Contribution to journal › Article › peer-review

Oyagbemi, AA, Adejumobi, OA, Jarikre, TA, Ajani, OS, Asenuga, ER, Gbadamosi, IT, Adedapo, ADA, Aro, AO, Ogunpolu, BS, Hassan, FO, Falayi, OO, Ogunmiluyi, IO, Omobowale, TO, Arojojoye, OA, Ola-Davies, OE, Saba, AB, Adedapo, AA, Emikpe, BO, Oyeyemi, MO, Nkadimeng, SM, McGaw, LJ, Kayoka-Kabongo, PN, Oguntibeju, OO & Yakubu, MA 2022, 'Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity', Biological Trace Element Research, vol. 200, no. 3, pp. 1220-1236. https://doi.org/10.1007/s12011-021-02722-1

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author = "Oyagbemi, {Ademola Adetokunbo} and Adejumobi, {Olumuyiwa Abiola} and Jarikre, {Theophilus Aghogho} and Ajani, {Olumide Samuel} and Asenuga, {Ebunoluwa Racheal} and Gbadamosi, {Idayat Titilayo} and Adedapo, {Aduragbenro Deborah A.} and Aro, {Abimbola Obemisola} and Ogunpolu, {Blessing Seun} and Hassan, {Fasilat Oluwakemi} and Falayi, {Olufunke Olubunmi} and Ogunmiluyi, {Iyanuoluwa Omolola} and Omobowale, {Temidayo Olutayo} and Arojojoye, {Oluwatosin Adetola} and Ola-Davies, {Olufunke Eunice} and Saba, {Adebowale Benard} and Adedapo, {Adeolu Alex} and Emikpe, {Benjamin Obukowho} and Oyeyemi, {Matthew Olugbenga} and Nkadimeng, {Sanah Malomile} and McGaw, {Lyndy Joy} and Kayoka-Kabongo, {Prudence Ngalula} and Oguntibeju, {Oluwafemi Omoniyi} and Yakubu, {Momoh Audu}",

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AU - Adejumobi, Olumuyiwa Abiola

AU - Jarikre, Theophilus Aghogho

AU - Ajani, Olumide Samuel

AU - Asenuga, Ebunoluwa Racheal

AU - Gbadamosi, Idayat Titilayo

AU - Adedapo, Aduragbenro Deborah A.

AU - Aro, Abimbola Obemisola

AU - Ogunpolu, Blessing Seun

AU - Hassan, Fasilat Oluwakemi

AU - Falayi, Olufunke Olubunmi

AU - Ogunmiluyi, Iyanuoluwa Omolola

AU - Omobowale, Temidayo Olutayo

AU - Arojojoye, Oluwatosin Adetola

AU - Ola-Davies, Olufunke Eunice

AU - Saba, Adebowale Benard

AU - Adedapo, Adeolu Alex

AU - Emikpe, Benjamin Obukowho

AU - Oyeyemi, Matthew Olugbenga

AU - Nkadimeng, Sanah Malomile

AU - McGaw, Lyndy Joy

AU - Kayoka-Kabongo, Prudence Ngalula

AU - Oguntibeju, Oluwafemi Omoniyi

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PY - 2022/3

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KW - Apoptosis

KW - Cell signalling

KW - Hypertension

KW - Oxidative stress

KW - Sodium fluoride toxicity

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Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity

ASJC Scopus Subject Areas

Keywords

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