Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives

Chelliah Selvam; Ramasamy Thilagavathi; Balasubramanian Narasimhan; Pradeep Kumar; Brian C. Jordan; Kasturi Ranganna

doi:10.1016/j.bmcl.2016.01.051

Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives

Chelliah Selvam, Ramasamy Thilagavathi, Balasubramanian Narasimhan, Pradeep Kumar, Brian C. Jordan, Kasturi Ranganna

Texas Southern University

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1140-1144
Number of pages	5
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	26
Issue number	4
DOIs	https://doi.org/10.1016/j.bmcl.2016.01.051
State	Published - Feb 15 2016

ASJC Scopus Subject Areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Keywords

3-D QSAR
Aryl ethers
CoMFA
mGluR5
Negative allosteric modulators

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10.1016/j.bmcl.2016.01.051

Cite this

Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives. / Selvam, Chelliah; Thilagavathi, Ramasamy; Narasimhan, Balasubramanian et al.
In: Bioorganic and Medicinal Chemistry Letters, Vol. 26, No. 4, 15.02.2016, p. 1140-1144.

Research output: Contribution to journal › Article › peer-review

Selvam, C, Thilagavathi, R, Narasimhan, B, Kumar, P, Jordan, BC & Ranganna, K 2016, 'Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives', Bioorganic and Medicinal Chemistry Letters, vol. 26, no. 4, pp. 1140-1144. https://doi.org/10.1016/j.bmcl.2016.01.051

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Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives

ASJC Scopus Subject Areas

Keywords

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