Histone deacetylase inhibitors as multitarget-directed epi-drugs in blocking pi3k oncogenic signaling: A polypharmacology approach

Kasturi Ranganna; Chelliah Selvam; Amruthesh Shivachar; Zivar Yousefipour

doi:10.3390/ijms21218198

Histone deacetylase inhibitors as multitarget-directed epi-drugs in blocking pi3k oncogenic signaling: A polypharmacology approach

Kasturi Ranganna, Chelliah Selvam, Amruthesh Shivachar, Zivar Yousefipour

Research output: Contribution to journal › Review article › peer-review

Original language	English
Article number	8198
Pages (from-to)	1-27
Number of pages	27
Journal	International Journal of Molecular Sciences
Volume	21
Issue number	21
DOIs	https://doi.org/10.3390/ijms21218198
State	Published - Nov 1 2020

ASJC Scopus Subject Areas

Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

Keywords

CUDC-907
Epigenetics
HDAC-PI3K hybrid molecule
Histone deacetylase
Histone deacetylase inhibitors
Phosphatidylinositol kinase

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10.3390/ijms21218198

Cite this

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title = "Histone deacetylase inhibitors as multitarget-directed epi-drugs in blocking pi3k oncogenic signaling: A polypharmacology approach",

keywords = "CUDC-907, Epigenetics, HDAC-PI3K hybrid molecule, Histone deacetylase, Histone deacetylase inhibitors, Phosphatidylinositol kinase",

author = "Kasturi Ranganna and Chelliah Selvam and Amruthesh Shivachar and Zivar Yousefipour",

note = "Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2020",

month = nov,

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doi = "10.3390/ijms21218198",

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T1 - Histone deacetylase inhibitors as multitarget-directed epi-drugs in blocking pi3k oncogenic signaling

T2 - A polypharmacology approach

AU - Ranganna, Kasturi

AU - Selvam, Chelliah

AU - Shivachar, Amruthesh

AU - Yousefipour, Zivar

PY - 2020/11/1

Y1 - 2020/11/1

KW - CUDC-907

KW - Epigenetics

KW - HDAC-PI3K hybrid molecule

KW - Histone deacetylase

KW - Histone deacetylase inhibitors

KW - Phosphatidylinositol kinase

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U2 - 10.3390/ijms21218198

DO - 10.3390/ijms21218198

M3 - Review article

C2 - 33147762

AN - SCOPUS:85094893426

SN - 1661-6596

VL - 21

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EP - 27

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

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Histone deacetylase inhibitors as multitarget-directed epi-drugs in blocking pi3k oncogenic signaling: A polypharmacology approach

ASJC Scopus Subject Areas

Keywords

Access to Document

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