Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk

Siddhartha P. Kar; Jonathan P. Tyrer; Qiyuan Li; Kate Lawrenson; Katja K.H. Aben; Hoda Anton-Culver; Natalia Antonenkova; Georgia Chenevix-Trench; Helen Baker; Elisa V. Bandera; Yukie T. Bean; Matthias W. Beckmann; Andrew Berchuck; Maria Bisogna; Line Bjørge; Natalia Bogdanova; Louise Brinton; Angela Brooks-Wilson; Ralf Butzow; Ian Campbell; Karen Carty; Jenny Chang-Claude; Yian Ann Chen; Zhihua Chen; Linda S. Cook; Daniel Cramer; Julie M. Cunningham; Cezary Cybulski; Agnieszka Dansonka-Mieszkowska; Joe Dennis; Ed Dicks; Jennifer A. Doherty; Thilo Dörk; Andreas Du Bois; Matthias Dürst; Diana Eccles; Douglas F. Easton; Robert P. Edwards; Arif B. Ekici; Peter A. Fasching; Brooke L. Fridley; Yu Tang Gao; Aleksandra Gentry-Maharaj; Graham G. Giles; Rosalind Glasspool; Ellen L. Goode; Marc T. Goodman; Jacek Grownwald; Patricia Harrington; Philipp Harter; Alexander Hein; Florian Heitz; Michelle A.T. Hildebrandt; Peter Hillemanns; Estrid Hogdall; Claus K. Hogdall; Satoyo Hosono; Edwin S. Iversen; Anna Jakubowska; James Paul; Allan Jensen; Bu Tian Ji; Beth Y. Karlan; Susanne K. Kjaer; Linda E. Kelemen; Melissa Kellar; Joseph Kelley; Lambertus A. Kiemeney; Camilla Krakstad; Jolanta Kupryjanczyk; Diether Lambrechts; Sandrina Lambrechts; Nhu D. Le; Alice W. Lee; Shashi Lele; Arto Leminen; Jenny Lester; Douglas A. Levine; Dong Liang; Jolanta Lissowska; Karen Lu; Jan Lubinski; Lene Lundvall; Leon Massuger; Keitaro Matsuo; Valerie McGuire; John R. McLaughlin; Iain A. McNeish; Usha Menon; Francesmary Modugno; Kirsten B. Moysich; Steven A. Narod; Lotte Nedergaard; Roberta B. Ness; Heli Nevanlinna; Kunleodunsi; Sara H. Olson; Irene Orlow; Sandra Orsulic; Rachel Palmieri Weber; Celeste Leigh Pearce; Tanja Pejovic; Liisa M. Pelttari; Jennifer Permuth-Wey; Catherine M. Phelan; Malcolm C. Pike; Elizabeth M. Poole; Susan J. Ramus; Harvey A. Risch; Barry Rosen; Mary Anne Rossing; Joseph H. Rothstein; Anja Rudolph; Ingo B. Runnebaum; Iwona K. Rzepecka; Helga B. Salvesen; Joellen M. Schildkraut; Ira Schwaab; Xiao Ou Shu; Yurii B. Shvetsov; Nadeem Siddiqui; Weiva Sieh; Honglin Song; Melissa C. Southey; Lara E. Sucheston-Campbell; Ingvild L. Tangen; Soo Hwang Teo; Kathryn L. Terry; Pamela J. Thompson; Agnieszka Timorek; Ya Yu Tsai; Shelley S. Tworoger; Anne M. Van Altena; Els Van Nieuwenhuysen; Ignace Vergote; Robert A. Vierkant; Shan Wang-Gohrke; Christine Walsh; Nicolas Wentzensen; Alice S. Whittemore; Kristine G. Wicklund; Lynne R. Wilkens; Yin Ling Woo; Xifeng Wu; Anna Wu; Hannah Yang; Wei Zheng; Argyrios Ziogas; Thomas A. Sellers; Alvaro N.A. Monteiro; Matthew L. Freedman; Simon A. Gayther; Paul D.P. Pharoah

doi:10.1158/1055-9965.EPI-14-1270

Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk

Siddhartha P. Kar, Jonathan P. Tyrer, Qiyuan Li, Kate Lawrenson, Katja K.H. Aben, Hoda Anton-Culver, Natalia Antonenkova, Georgia Chenevix-Trench, Helen Baker, Elisa V. Bandera, Yukie T. Bean, Matthias W. Beckmann, Andrew Berchuck, Maria Bisogna, Line Bjørge, Natalia Bogdanova, Louise Brinton, Angela Brooks-Wilson, Ralf Butzow, Ian CampbellKaren Carty, Jenny Chang-Claude, Yian Ann Chen, Zhihua Chen, Linda S. Cook, Daniel Cramer, Julie M. Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Joe Dennis, Ed Dicks, Jennifer A. Doherty, Thilo Dörk, Andreas Du Bois, Matthias Dürst, Diana Eccles, Douglas F. Easton, Robert P. Edwards, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Yu Tang Gao, Aleksandra Gentry-Maharaj, Graham G. Giles, Rosalind Glasspool, Ellen L. Goode, Marc T. Goodman, Jacek Grownwald, Patricia Harrington, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A.T. Hildebrandt, Peter Hillemanns, Estrid Hogdall, Claus K. Hogdall, Satoyo Hosono, Edwin S. Iversen, Anna Jakubowska, James Paul, Allan Jensen, Bu Tian Ji, Beth Y. Karlan, Susanne K. Kjaer, Linda E. Kelemen, Melissa Kellar, Joseph Kelley, Lambertus A. Kiemeney, Camilla Krakstad, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Alice W. Lee, Shashi Lele, Arto Leminen, Jenny Lester, Douglas A. Levine, Dong Liang, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon Massuger, Keitaro Matsuo, Valerie McGuire, John R. McLaughlin, Iain A. McNeish, Usha Menon, Francesmary Modugno, Kirsten B. Moysich, Steven A. Narod, Lotte Nedergaard, Roberta B. Ness, Heli Nevanlinna, Kunleodunsi, Sara H. Olson, Irene Orlow, Sandra Orsulic, Rachel Palmieri Weber, Celeste Leigh Pearce, Tanja Pejovic, Liisa M. Pelttari, Jennifer Permuth-Wey, Catherine M. Phelan, Malcolm C. Pike, Elizabeth M. Poole, Susan J. Ramus, Harvey A. Risch, Barry Rosen, Mary Anne Rossing, Joseph H. Rothstein, Anja Rudolph, Ingo B. Runnebaum, Iwona K. Rzepecka, Helga B. Salvesen, Joellen M. Schildkraut, Ira Schwaab, Xiao Ou Shu, Yurii B. Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C. Southey, Lara E. Sucheston-Campbell, Ingvild L. Tangen, Soo Hwang Teo, Kathryn L. Terry, Pamela J. Thompson, Agnieszka Timorek, Ya Yu Tsai, Shelley S. Tworoger, Anne M. Van Altena, Els Van Nieuwenhuysen, Ignace Vergote, Robert A. Vierkant, Shan Wang-Gohrke, Christine Walsh, Nicolas Wentzensen, Alice S. Whittemore, Kristine G. Wicklund, Lynne R. Wilkens, Yin Ling Woo, Xifeng Wu, Anna Wu, Hannah Yang, Wei Zheng, Argyrios Ziogas, Thomas A. Sellers, Alvaro N.A. Monteiro, Matthew L. Freedman, Simon A. Gayther, Paul D.P. Pharoah

Texas Southern University

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1574-1584
Number of pages	11
Journal	Cancer Epidemiology Biomarkers and Prevention
Volume	24
Issue number	10
DOIs	https://doi.org/10.1158/1055-9965.EPI-14-1270
State	Published - Oct 1 2015

ASJC Scopus Subject Areas

General Medicine

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10.1158/1055-9965.EPI-14-1270

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Kar, S. P., Tyrer, J. P., Li, Q., Lawrenson, K., Aben, K. K. H., Anton-Culver, H., Antonenkova, N., Chenevix-Trench, G., Baker, H., Bandera, E. V., Bean, Y. T., Beckmann, M. W., Berchuck, A., Bisogna, M., Bjørge, L., Bogdanova, N., Brinton, L., Brooks-Wilson, A., Butzow, R., ... Pharoah, P. D. P. (2015). Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk. Cancer Epidemiology Biomarkers and Prevention, 24(10), 1574-1584. https://doi.org/10.1158/1055-9965.EPI-14-1270

Kar, SP, Tyrer, JP, Li, Q, Lawrenson, K, Aben, KKH, Anton-Culver, H, Antonenkova, N, Chenevix-Trench, G, Baker, H, Bandera, EV, Bean, YT, Beckmann, MW, Berchuck, A, Bisogna, M, Bjørge, L, Bogdanova, N, Brinton, L, Brooks-Wilson, A, Butzow, R, Campbell, I, Carty, K, Chang-Claude, J, Chen, YA, Chen, Z, Cook, LS, Cramer, D, Cunningham, JM, Cybulski, C, Dansonka-Mieszkowska, A, Dennis, J, Dicks, E, Doherty, JA, Dörk, T, Du Bois, A, Dürst, M, Eccles, D, Easton, DF, Edwards, RP, Ekici, AB, Fasching, PA, Fridley, BL, Gao, YT, Gentry-Maharaj, A, Giles, GG, Glasspool, R, Goode, EL, Goodman, MT, Grownwald, J, Harrington, P, Harter, P, Hein, A, Heitz, F, Hildebrandt, MAT, Hillemanns, P, Hogdall, E, Hogdall, CK, Hosono, S, Iversen, ES, Jakubowska, A, Paul, J, Jensen, A, Ji, BT, Karlan, BY, Kjaer, SK, Kelemen, LE, Kellar, M, Kelley, J, Kiemeney, LA, Krakstad, C, Kupryjanczyk, J, Lambrechts, D, Lambrechts, S, Le, ND, Lee, AW, Lele, S, Leminen, A, Lester, J, Levine, DA, Liang, D, Lissowska, J, Lu, K, Lubinski, J, Lundvall, L, Massuger, L, Matsuo, K, McGuire, V, McLaughlin, JR, McNeish, IA, Menon, U, Modugno, F, Moysich, KB, Narod, SA, Nedergaard, L, Ness, RB, Nevanlinna, H, Kunleodunsi, Olson, SH, Orlow, I, Orsulic, S, Weber, RP, Pearce, CL, Pejovic, T, Pelttari, LM, Permuth-Wey, J, Phelan, CM, Pike, MC, Poole, EM, Ramus, SJ, Risch, HA, Rosen, B, Rossing, MA, Rothstein, JH, Rudolph, A, Runnebaum, IB, Rzepecka, IK, Salvesen, HB, Schildkraut, JM, Schwaab, I, Shu, XO, Shvetsov, YB, Siddiqui, N, Sieh, W, Song, H, Southey, MC, Sucheston-Campbell, LE, Tangen, IL, Teo, SH, Terry, KL, Thompson, PJ, Timorek, A, Tsai, YY, Tworoger, SS, Van Altena, AM, Van Nieuwenhuysen, E, Vergote, I, Vierkant, RA, Wang-Gohrke, S, Walsh, C, Wentzensen, N, Whittemore, AS, Wicklund, KG, Wilkens, LR, Woo, YL, Wu, X, Wu, A, Yang, H, Zheng, W, Ziogas, A, Sellers, TA, Monteiro, ANA, Freedman, ML, Gayther, SA & Pharoah, PDP 2015, 'Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk', Cancer Epidemiology Biomarkers and Prevention, vol. 24, no. 10, pp. 1574-1584. https://doi.org/10.1158/1055-9965.EPI-14-1270

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note = "Publisher Copyright: {\textcopyright} 2015 American Association for Cancer Research.",

year = "2015",

month = oct,

day = "1",

doi = "10.1158/1055-9965.EPI-14-1270",

language = "English",

volume = "24",

pages = "1574--1584",

journal = "Cancer Epidemiology Biomarkers and Prevention",

issn = "1055-9965",

number = "10",

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T1 - Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk

AU - Kar, Siddhartha P.

AU - Tyrer, Jonathan P.

AU - Li, Qiyuan

AU - Lawrenson, Kate

AU - Aben, Katja K.H.

AU - Anton-Culver, Hoda

AU - Antonenkova, Natalia

AU - Chenevix-Trench, Georgia

AU - Baker, Helen

AU - Bandera, Elisa V.

AU - Bean, Yukie T.

AU - Beckmann, Matthias W.

AU - Berchuck, Andrew

AU - Bisogna, Maria

AU - Bjørge, Line

AU - Bogdanova, Natalia

AU - Brinton, Louise

AU - Brooks-Wilson, Angela

AU - Butzow, Ralf

AU - Campbell, Ian

AU - Carty, Karen

AU - Chang-Claude, Jenny

AU - Chen, Yian Ann

AU - Chen, Zhihua

AU - Cook, Linda S.

AU - Cramer, Daniel

AU - Cunningham, Julie M.

AU - Cybulski, Cezary

AU - Dansonka-Mieszkowska, Agnieszka

AU - Dennis, Joe

AU - Dicks, Ed

AU - Doherty, Jennifer A.

AU - Dörk, Thilo

AU - Du Bois, Andreas

AU - Dürst, Matthias

AU - Eccles, Diana

AU - Easton, Douglas F.

AU - Edwards, Robert P.

AU - Ekici, Arif B.

AU - Fasching, Peter A.

AU - Fridley, Brooke L.

AU - Gao, Yu Tang

AU - Gentry-Maharaj, Aleksandra

AU - Giles, Graham G.

AU - Glasspool, Rosalind

AU - Goode, Ellen L.

AU - Goodman, Marc T.

AU - Grownwald, Jacek

AU - Harrington, Patricia

AU - Harter, Philipp

AU - Hein, Alexander

AU - Heitz, Florian

AU - Hildebrandt, Michelle A.T.

AU - Hillemanns, Peter

AU - Hogdall, Estrid

AU - Hogdall, Claus K.

AU - Hosono, Satoyo

AU - Iversen, Edwin S.

AU - Jakubowska, Anna

AU - Paul, James

AU - Jensen, Allan

AU - Ji, Bu Tian

AU - Karlan, Beth Y.

AU - Kjaer, Susanne K.

AU - Kelemen, Linda E.

AU - Kellar, Melissa

AU - Kelley, Joseph

AU - Kiemeney, Lambertus A.

AU - Krakstad, Camilla

AU - Kupryjanczyk, Jolanta

AU - Lambrechts, Diether

AU - Lambrechts, Sandrina

AU - Le, Nhu D.

AU - Lee, Alice W.

AU - Lele, Shashi

AU - Leminen, Arto

AU - Lester, Jenny

AU - Levine, Douglas A.

AU - Liang, Dong

AU - Lissowska, Jolanta

AU - Lu, Karen

AU - Lubinski, Jan

AU - Lundvall, Lene

AU - Massuger, Leon

AU - Matsuo, Keitaro

AU - McGuire, Valerie

AU - McLaughlin, John R.

AU - McNeish, Iain A.

AU - Menon, Usha

AU - Modugno, Francesmary

AU - Moysich, Kirsten B.

AU - Narod, Steven A.

AU - Nedergaard, Lotte

AU - Ness, Roberta B.

AU - Nevanlinna, Heli

AU - Kunleodunsi,

AU - Olson, Sara H.

AU - Orlow, Irene

AU - Orsulic, Sandra

AU - Weber, Rachel Palmieri

AU - Pearce, Celeste Leigh

AU - Pejovic, Tanja

AU - Pelttari, Liisa M.

AU - Permuth-Wey, Jennifer

AU - Phelan, Catherine M.

AU - Pike, Malcolm C.

AU - Poole, Elizabeth M.

AU - Ramus, Susan J.

AU - Risch, Harvey A.

AU - Rosen, Barry

AU - Rossing, Mary Anne

AU - Rothstein, Joseph H.

AU - Rudolph, Anja

AU - Runnebaum, Ingo B.

AU - Rzepecka, Iwona K.

AU - Salvesen, Helga B.

AU - Schildkraut, Joellen M.

AU - Schwaab, Ira

AU - Shu, Xiao Ou

AU - Shvetsov, Yurii B.

AU - Siddiqui, Nadeem

AU - Sieh, Weiva

AU - Song, Honglin

AU - Southey, Melissa C.

AU - Sucheston-Campbell, Lara E.

AU - Tangen, Ingvild L.

AU - Teo, Soo Hwang

AU - Terry, Kathryn L.

AU - Thompson, Pamela J.

AU - Timorek, Agnieszka

AU - Tsai, Ya Yu

AU - Tworoger, Shelley S.

AU - Van Altena, Anne M.

AU - Van Nieuwenhuysen, Els

AU - Vergote, Ignace

AU - Vierkant, Robert A.

AU - Wang-Gohrke, Shan

AU - Walsh, Christine

AU - Wentzensen, Nicolas

AU - Whittemore, Alice S.

AU - Wicklund, Kristine G.

AU - Wilkens, Lynne R.

AU - Woo, Yin Ling

AU - Wu, Xifeng

AU - Wu, Anna

AU - Yang, Hannah

AU - Zheng, Wei

AU - Ziogas, Argyrios

AU - Sellers, Thomas A.

AU - Monteiro, Alvaro N.A.

AU - Freedman, Matthew L.

AU - Gayther, Simon A.

AU - Pharoah, Paul D.P.

PY - 2015/10/1

Y1 - 2015/10/1

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U2 - 10.1158/1055-9965.EPI-14-1270

DO - 10.1158/1055-9965.EPI-14-1270

M3 - Article

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AN - SCOPUS:84942870326

SN - 1055-9965

VL - 24

SP - 1574

EP - 1584

JO - Cancer Epidemiology Biomarkers and Prevention

JF - Cancer Epidemiology Biomarkers and Prevention

IS - 10

ER -

Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk

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