Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice

Zhen Yang; Wei Zhu; Song Gao; Haiyan Xu; Baojian Wu; Kaustubh Kulkarni; Rashim Singh; Lan Tang; Ming Hu

doi:10.1016/j.jpba.2010.03.011

Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice

Zhen Yang, Wei Zhu, Song Gao, Haiyan Xu, Baojian Wu, Kaustubh Kulkarni, Rashim Singh, Lan Tang, Ming Hu

University of Houston

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	81-89
Number of pages	9
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	53
Issue number	1
DOIs	https://doi.org/10.1016/j.jpba.2010.03.011
State	Published - Sep 2010
Externally published	Yes

ASJC Scopus Subject Areas

Analytical Chemistry
Pharmaceutical Science
Drug Discovery
Spectroscopy
Clinical Biochemistry

Keywords

Genistein
Pharmacokinetics
Phase II metabolites
UPLC-MS/MS

Access to Document

10.1016/j.jpba.2010.03.011

Cite this

Yang, Z., Zhu, W., Gao, S., Xu, H., Wu, B., Kulkarni, K., Singh, R., Tang, L., & Hu, M. (2010). Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice. Journal of Pharmaceutical and Biomedical Analysis, 53(1), 81-89. https://doi.org/10.1016/j.jpba.2010.03.011

Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice. / Yang, Zhen; Zhu, Wei; Gao, Song et al.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 53, No. 1, 09.2010, p. 81-89.

Research output: Contribution to journal › Article › peer-review

Yang, Z, Zhu, W, Gao, S, Xu, H, Wu, B, Kulkarni, K, Singh, R, Tang, L & Hu, M 2010, 'Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice', Journal of Pharmaceutical and Biomedical Analysis, vol. 53, no. 1, pp. 81-89. https://doi.org/10.1016/j.jpba.2010.03.011

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keywords = "Genistein, Pharmacokinetics, Phase II metabolites, UPLC-MS/MS",

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AU - Tang, Lan

AU - Hu, Ming

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Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice

ASJC Scopus Subject Areas

Keywords

Access to Document

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